UC Santa Barbara General CatalogUniversity of California, Santa Barbara

Molecular, Cellular, and Developmental Biology

Division of Mathematical, Life, and Physical Sciences
Life Sciences & Technology Building, Rm. 3308
Telephone: (805) 893-3512
Undergraduate Information (805) 893-5191
Graduate Information (805) 893-8499
Undergraduate e-mail: mcdb-ugrad@lifesci.ucsb.edu
Graduate e-mail: mcdb-gradasst@lifesci.ucsb.edu
Website: lifesci.ucsb.edu/MCDB
Department Chair:  Joel H. Rothman


 

Some courses displayed may not be offered every year. For actual course offerings by quarter, please consult the Quarterly Class Search or GOLD (for current students). To see the historical record of when a particular course has been taught in the past, please visit the Course Enrollment Histories.

Molecular, Cellular & Develop. Biology
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MCDB 1A. Introductory Biology I
(4) STAFF
Prerequisite: Chemistry 1A-B-C (Chem 1C may be taken concurrently), or a score of 4 or better on either the Advanced Placement Chemistry or Advanced Placement Biology exams.
Enrollment Comments: Not open for credit to students who have completed Biology 4A or MCDB 4A or5A.
Introduction to biochemistry, cell biology and development, and genetics.
MCDB 1AL. Introductory Biology Laboratory I
(1) STAFF
Prerequisite: MCDB 1A (may be taken concurrently).
Enrollment Comments: Not open for credit students who have completed Biology 4A or MCDB 4A or 5AL.
Laboratory investigations illustrate basic principles of biochemistry, molecular and cell biology, development, and genetics.
MCDB 1AZ. Selected Topics from MCDB 1A
(1-3) STAFF
Prerequisite: Consent of department.
Enrollment Comments: Not open for credit to students who have completed Biology 4AZ or MCDB 4AZ or 5AZ.
Designed for transfer students who have completed part of MCDB 1A through transfer work. Topics will be selected by the department, as appropriate, to fulfill the introductory biology requirement at UCSB.
MCDB 1B. Introductory Biology II--Physiology
(3) STAFF
Prerequisite: MCDB 1A and Chemistry 1A-B-C; or MCDB 1A with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 4B or EEMB 4B or 5B or MCDB 4B or 5B.
Introduction to animal and plant physiology.
MCDB 1BL. Introductory Biology Laboratory II
(1) STAFF
Prerequisite: MCDB 1A; and, concurrent enrollment in MCDB 1B and EEMB 2.
Enrollment Comments: Not open for credit to students who have completed Biology 4B or EEMB 4B or5BL or MCDB 4B or 5BL. Same course as EEMB 2L.
Laboratory investigations illustrate basic principles of animal and plant physiology, ecology, and evolution.
MCDB 1BZ. Selected Topics from MCDB 1B
(1-2) STAFF
Prerequisite: Consent of department.
Enrollment Comments: Not open for credit to students who have completed Biology 4BZ or EEMB 4BZ or 5BZ or MCDB 4BZ or 5BZ.
Designed for transfer students who have completed part of MCDB 1B through transfer work. Topics will be selected by the department, as appropriate, to fulfill the introductory biology requirement at UCSB.
MCDB 20. Concepts of Biology
(4) LOW, THROWER
Enrollment Comments: Open to non-majors. Not open for credit toward graduation to students who have completed Natural Science 1C. Not open for credit to students who have completed Biology 20, or Biology 4A-B-C, or MCDB 5A-AL, or EEMB 5B-BL, or MCDB 5B-BL,or EEMB 5C-CL, or MCDB 1A, or MCDB 1B, or EEMB 2, or EEMB 3, or EEMB 20.
Introduction to the science of life; cells, genetics, metabolism, molecular biology, physiology, natural selection, evolution, ecosystems; current news and controversial topics in biology.
MCDB 21. The Immune System and Aids
(4) LOW
Enrollment Comments: Not open for credit to students who have completed Biology 21.
The basic properties of the immune system; the basic biology of aids and AIDS virus infection; and the biology of other sexually transmitted diseases.
MCDB 23. Biology of Cancer
(3) KOHL
An introduction to developments regarding the etiology and treatment of various cancers. Lectures compare normal cells and tissues with those whichhave become malignnant. Discussion of causes, treatment, and prevention of specific cancers.
MCDB 24. Genetics and Human Disease
(3) KOHL
Introduction to genetics with emphasis on humans. Topics focus on human diseases with strong evidence for genetic components. Diseases covered include cancer, cystic fibrosis, Huntington's, muscular dystrophy, and others.
MCDB 26. Contemporary Nutrition
(4) STAFF
Presents the scientific basis for human nutrition including dietary nutrients and requirements, energy balance in health and disease, and needs of various life stages. Food safety, preservation, and undernutrition throughout the world is discussed.
MCDB 27. Memory: Bridging the Humanities and Neuroscience
(3) KOSIK, JULLIEN
Enrollment Comments: Same course as French 40X and Comparative Literature 27.
Neurosciences now ask some of the same profound questions posed by writers, artists and philosophers for centuries, thus opening surprising perspectives on memory and morality, dreams and perception, identity and agency. This course explores this emerging concordance.
MCDB 29. Fundamentals of Biomedical Research
(3) FOLTZ
Recommended Preparation: High School Biology.
Enrollment Comments: Open to non-majors. Quarters usually offered: Winter.
Basics of the scientific method as applied to basic biomedical research; examples of how basic research influences human health. Students will develop the intellectual tools to deconstruct primary literature and interpret data.
MCDB 84. Internship in Biological Sciences
(1-5) STAFF
Prerequisite: Lower-division standing; instructor and departmental approval required.
Enrollment Comments: Quarters usually offered: Winter, Spring, Summer, Fall. Students must have a 2.5 cumulative grade-point average. May be repeated for credit to a maximum of 15 units, but no units may be applied toward the major.
Opportunity to obtain practical biological-related research experience by working under faculty direction as an intern with local, state, federal, or private agencies. A written report will be submitted for evaluation.
MCDB 90A. Honors Forum in Molecular, Cellular, Developmental Biology
(2) FOLTZ
Prerequisite: Honors standing in College of Letters and Science and consent of instructor
Seminar for selected students in molecular, cellular, and developmental biology. Students will be introduced to research opportunities in the department. Focus will center on the use of the science library and the internet as tools to produce a basic research paper.
MCDB 90B. Honors Forum in Molecular, Cellular, Developmental Biology
(2) STAFF
Prerequisite: Honors standing in College of Letters and Science and consent of instructor
Continuation of MCDB 90A. Students are introduced to various faculty in thedepartment and begin reading and reviewing some of the original literature in the field. Students are expected to critically analyze basic research papers.
MCDB 90C. Honors Forum in Molecular, Cellular, Developmental Biology
(2) STAFF
Prerequisite: Honors standing in College of Letters and Science and consent of instructor
Continuation of MCDB 90B. Students meet with selected faculty in a defined area of research interest, attend various research seminars and laboratory meetings, and begin involving themselves with a research group.
MCDB 92. Special Topics in Biology
(1-4) STAFF
Enrollment Comments: May be repeated for credit to a maximum of 4 units.
Special topics in molecular, cellular, and developmental biology. Course content varies. Information may be obtained in department office.
MCDB 98. Readings in Biology
(1-3) STAFF
Prerequisite: Consent of instructor and department.
Enrollment Comments: Students are required to have a minimum 3.0 cumulative grade-point average and are limited to 5 units per quarter and 30 units total in all 98/99/198/199/199AA-ZZ courses combined. Students are limited to 6 units of Biology 98 and MCDB 98 combined. Maximum of 3 units/quarter.
Special readings on selected topics in biology. Individual conferences one hour every week. Designed to broaden the outlook and experience of advanced lower-division students. Hours and credit by arrangement with any member of the staff.
MCDB 99. Introduction to Research
(1-3) STAFF
Prerequisite: Consent of instructor and department.
Enrollment Comments: Students are required to have a minimum 3.0 cumulative grade-point average and are limited to 5 units per quarter and 30 units total in all 98/99/198/199/199AA-ZZ courses combined. Students are limited to 6 units of Biology 99 and MCDB 99 combined. Maximum of 3 units/quarter.
Laboratory experience for advanced lower-division students. Hours and credit by arrangement with any member of the staff.
Collapse Courses Upper Division 
MCDB 101A. Molecular Genetics I: Prokaryotes
(4) LOW, THROWER
Prerequisite: MCDB 1A-B, EEMB 2; and, Chemistry 1A-B-C; completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 130A.
From the double helix and genetic code to the latest breakthroughs. Structure, function, evolution and manipulation of DNA, RNA. Replication, expression, recombination, complementation, and their regulation in prakaryotes (bacteria, plasmids, viruses). Recombinant DNA technology in medicine, research, agriculture and industry.
MCDB 101AH. Molecular Genetics I: Prokaryotes - Honors
(1) DAVID LOW, DOUG THROWER
Prerequisite: Concurrent enrollment in MCDB 101A; consent of instructor.
Honors section designed to permit an in-depth analysis of topics relating to genetics.
MCDB 101B. Molecular Genetics II: Eukaryotes
(4) POOLE, CHRISTOFFERSEN
Prerequisite: MCDB 1A, EEMB 2 and MCDB 1B, and MCDB 101A. Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Quarters usually offered: Winter, Spring, Summer. Not open for credit to students who have completed Biology 130B.
Mendelian and molecular genetics. Replication, recombination, transmission and expression of DNA in eukaryotic organisms from yeast to man. Uses of traditional genetics and modern molecular techniques, including molecular genetic approaches to the study of human disease.
MCDB 103. Cell Biology
(4) MARTH, MA
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B. Completion of all listed prerequisites wita grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 137.
An introduction to the structure and function of cell organelles; membranes, nucleus, mitochondria, chloroplasts, endoplasmic reticulum, golgi apparatus, lysosomes, microbodies, microtubules, cilia, centrioles, and microfilaments.
MCDB 103L. Laboratory in Molecular Cell Biology
(4) MA
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B, and MCDB 103 (may be taken concurrently). Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 137L.
Laboratory techniques of modern cell biology; molecular dissection of cell structure and function.
MCDB 108A. General Biochemistry
(4) SEARS
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B; and Chemistry 1A-B-C; and Chemistry 109A-B-C (Chem 109C may be taken concurrently). Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 108A. Not open for credit to students who have completed MCDB W 108A.
Repeat Comments: Students needing to repeat MCDB 108A due to a poor grade the first time, can repeat it either as MCDB 108A or MCDB W 108A. Only one repeat attempt between the 2 courses is allowed.
Introduction to the structures and functions of proteins, including enzymes, with emphasis on their basic architecture and biological mechanisms of action and regulation. Methods used for characterizing proteins and analyzing enzyme kinetic data are also emphasized.
MCDB 108AH. General Biochemistry--Honors
(1) SEARS
Prerequisite: MCDB 108A or MCDB W 108A (may be taken concurrently). Consent of instructor.
Enrollment Comments: Quarters usually offered: Fall.
Honors component of MCDB 108A or W108A designed to permit an in-depth consideration of selected aspects of the structure/function relationships of proteins and nucleic acids.
MCDB 108AL. Protein Structure/ Function Laboratory
(2) SEARS
Prerequisite: MCDB 108A or MCDB W 108A (may be taken concurrently).
Recommended Preparation: Mathematics 3A-B or 34A-B.
Enrollment Comments: Quarters usually offered: Fall.
Computer laboratory analysis of biochemical structures and the dynamics of their interactions with other molecules.
MCDB 108B. General Biochemistry
(4) LEW
Prerequisite: MCDB 108A or MCDB W 108A with a grade of C or better. Chem 109C with a grade of C or better.
Enrollment Comments: Quarters usually offered: Winter. Not open for credit to students who have completed Biology 108B.
Principles of human energy metabolism. Chemistry and physiology of the major metabolic pathways of energy production. Metabolic interrelationships of the major body organs. Applications to human nutrition and disease, exercise, starvation, obesity, and atherosclerosis.
MCDB 108C. General Biochemistry
(4) HAYES
Prerequisite: MCDB 108A-B with a grade of C or better. OR MCDB W 108A and MCDB 108B with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 108C.
Amino acid and nucleic acid metabolism, nucleic acid structure, biochemistry of lipids and biological membranes, photosynthesis, special topics.
MCDB 109L. Laboratory in Biochemistry
(4) POOLE
Prerequisite: MCDB 108A or MCDB W 108A or Chemistry 142A; and MCDB 1A-1B. Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Quarters usually offered: Spring. Not open for credit to students who have completed Biology 109L.
Laboratory techniques in biochemistry. Emphasis on techniques used in modern protein and nucleic acid biochemical research. Includes aspects of the use of computer analysis nd recombinant DNA techniques in modern biochemistry.
MCDB 110. Principles of Biochemistry
(4) ROTHMAN, LOW
Prerequisite: Chemistry 1A-B-C; and Chemistry 109A-B. Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not for specialized majors in molecular, cellular, and developmental biology, physiology, nor for students who have completed Biology 118A-B-C or MCDB 108A-B-C. Not open for credit to sutdents who have completed Biology 118.
An introduction to molecular structures and mechanisms of living systems.
MCDB 111. Human Physiology
(4) SMITH
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 100.
Fundamentals of human physiology at the molecular, cellular and organismal levels. Emphasis on homeostatic mechanisms regulating intercellular communication, muscle function, circulation, metabolism and body fluid balance/composition.
MCDB 111H. Human Physiology - Honors
(1) SMITH
Prerequisite: Concurrent enrollment in MCDB 111; consent of instructor.
Enrollment Comments: Quarters usually offered: Winter.
Honors section designed to permit an in-depth analysis of topics relating to fundamentals of human physiology at the molecular, cellular and organismal levels. Emphasis on homeostatic mechanisms regulating intercellular communication, muscle function, circulation, metabolism and body fluid balance/composition.
MCDB 112. Developmental Biology
(4) FOLTZ
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B, and EEMB 3; and MCDB 101A or EEMB 129. Completion of all listed prerequisties with a grade of C or better.
Enrollment Comments: Quarters usually offered: Fall. Not open for credit to students who have completed Zoology 100.
Modern aspects of animal development. Molecular and cellular mechanisms of embroygenesis.
MCDB 112H. Developmental Biology - Honors
(1) FOLTZ
Prerequisite: Concurrent enrollment in MCDB 112; consent of instructor.
Enrollment Comments: Quarters usually offered: Fall.
Honors section designed to permit an in-depth analysis of topics relating to the mechanisms of animal development, from single cells to the whole organism, using examples from vertebrates and invertebrates studied in terms of morphology, physiology, genetics and biochemistry.
MCDB 112L. Laboratory in Developmental Biology
(2) DE TOMASO
Prerequisite: MCDB 1A, EEMB 2 and MCDB 1B, and EEMB 3, and MCDB 101A, and concurrent enrollment in MCDB 112. Completion of all listed prerequisites with a gradeof C or better.
Enrollment Comments: Not open for credit to students who have completed Zoology 100L.
Modern laboratory techniques in developmental biology. Experimental aproaches to development using several animal model systems.
MCDB 118. Plant Development
(4) FINKELSTEIN
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B; and, MCDB 101A or EEMB 129. Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 112 or Botany 111.
Differentiation and morphogenesis of plants: mechanisms of cell-cell interactions.
MCDB 123. Experimental Strategies in Physical Biochemistry
(4) WAITE
Prerequisite: MCDB 108A or MCDB W 108A or Chemistry 142A with a grade of C or better.
Presentation of selected contemporary concepts and methodologies for determining the structure, size, shape, charge, and interactive behavior of biological macromolecules.
MCDB 126A. Basic Pharmacology
(4) THROWER
Prerequisite: MCDB 101A (may be taken concurrently) or Chemistry 142C; Chemistry 109A-B-CCompletion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed EEMB 126A.
Designed to provide the student with a comprehensive knowledge of the history and scope of pharmacology as a basic science. Emphasis on the principles of drug action and the relationship of pharmacology to physiology, chemistry, and biochemistry.
MCDB 126AL. Pharmacology Lab I
(4) STOYAN, THROWER
Prerequisite: MCDB 126A (may be taken concurrently).
Enrollment Comments: Not open for credit to students who have completed EEMB 126AL.
Analysis of drug sites and machanisms of action using isolated tissues, organs, and intact animal preparations.
MCDB 126B. Basic Pharmacology
(4) VANDENBERG
Prerequisite: MCDB 101A or Chemistry 142C; Chemistry 109A-B-C. Completion of all listed prerequisites with a grade of C or better.
Recommended Preparation: MCDB 108A.
Enrollment Comments: MCDB 108A is strongly recommended. Not open for credit to students who completed Biology 119B.
Receptor signaling mechanisms; pharmacology of neurotransmitter and hormone receptors; molecular and cellular mechanisms of drug-receptor interactions.
MCDB 126BH. Basic Pharmacology II: Hormone and Neurotransmitter Receptors and Signaling- Honors
(1) VANDENBERG
Prerequisite: Concurrent enrollment in MCDB 126B; consent of instructor.
Enrollment Comments: Quarters usually offered: Winter.
Honors section designed to permit an indepth analysis of topics relating to receptor signaling mechanisms; pharmacology of neurotransmitter and hormone receptors; molecular and cellular mechanisms of drug-receptor interactions.
MCDB 126BL. Pharmacology Laboratory II
(4) VANDENBERG, THROWER, STOYAN
Prerequisite: MCDB 126B (may be taken concurrently).
Enrollment Comments: Not open for credit to students who have completed Biology 119BL.
An introduction to molecular and biochemical techniques in pharmacology; drug-receptor binding; receptor isolation; pharmacokinetics; techniques to evaluate potency, concentration and effects of hormones and their receptors.
MCDB 126C. Basic Pharmacology
(4) WILSON, THROWER
Prerequisite: MCDB 101A or Chemistry 142C; Chemistry 109A-B-C. Completion of all listed prerequisites with a grade of C or better.
Recommended Preparation: MCDB 108A.
Enrollment Comments: MCDB 108A is strongly recommended. Not open for credit to students who havecompleted Biology 119C.
Fundamental principles of pharmacology, drug-receptor theory, biochemical mechanisms of action of drugs.
MCDB 131. General Microbiology
(4) COOPER
Prerequisite: MCDB 101A (may be taken concurrently); Chemistry 109A-B-C (Chem 109C may be taken concurrently), or Chemistry 109A-B and MCDB 110. Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 104 or 104A.
Focuses on the general biology in microbes, primarily prokaryotes. Topics include the structure, physiology, and development of microorganisms and microbial communities, their culture and control, microbial genomics & metagenomics, and the importance of diverse microbes in food, agriculture, ecology and medicine.
MCDB 131L. Laboratory in General Microbiology
(2) COOPER
Prerequisite: MCDB 131 (may be taken concurrently).
Enrollment Comments: Not open for credit to students who have completed Biology 104 or 104L.
Laboratory experiments dealing with the isolation, cultivation, and physiological, biochemical and genetic analysis of diverse microorganisms.
MCDB 132. Bacterial Pathogenesis
(3) MAHAN
Prerequisite: MCDB 101A with a grade of C or better.
Enrollment Comments: MCDB 131 recommended. Not open for credit to students who have completed Biology 128.
The mechanisms by which bacterial pathogens cause disease. Investigation of the bacterial gene products that are produced during infection to understand the metabolic, physiological, and genetic factors that contribute to the virulence of bacterial pathogens.
MCDB 132L. Bacterial Pathogenesis Laboratory
(3) MAHAN
Prerequisite: Concurrent enrollment in MCDB 132.
Enrollment Comments: Not open for credit to students who have completed Biology 128L.
The latest molecular, biochemical, and genetic techniques available for theidentification of microbial gene products that contribute to infection. Study of the regulatory parameters that govern their expression.
MCDB 133. Molecular and Cellular Immunobiology
(5) SEARS
Prerequisite: MCDB 101A with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 123.
Introduction to the current concepts of immunology. Emphasis on immunoglobulin structure and function, cell-cell cooperation in the immune response, and the role of major histocompatibility complex and cytokines in regulating immune responsiveness.
MCDB 133H. Immunobiology-Honors
(1) SEARS
Prerequisite: Concurrent enrollment in MCDB 133.
Honors component of MCDB 133 focusing on selected aspects of the immune system and its components using a web browser to run interactive computer assignments.
MCDB 133L. Molecular and Cellular Immunobiology Lab
(4) STOYAN
Prerequisite: MCDB 133 with a grade of C or better (may be taken concurrently).
Enrollment Comments: Not open for credit to students who have completed Biology 123L.
Introduction to modern laboratory methods in immunology; properties and characterization of immunoglobulins and immunoglobulin-secreting cells; introduction to hybridoma technology; characterization of effector and regulatory T cells using functional assays.
MCDB 134. General Animal Virology
(4) SAMUEL
Prerequisite: MCDB 101A or EEMB 129 with a grade of C or better.
An introduction to the biology of animal viruses with emphasis on the biochemical and biophysical properties of viruses; the mechanisms by which animal viruses replicate; the cellular effects of and response to viral infection; and selected aspects of medical virology.
MCDB 134H. General Animal Virology-Honors
(1) SAMUEL
Prerequisite: MCDB 101A; concurrent enrollment in MCDB 134. Completion of all prerequisites with a grade of C or better.
Honors virology course designed to permit an in-depth consideration and analysis of selected aspects of the biology and biochemistry of animal viruses, the mechanisms by which they replicate, and mechanisms of antiviral innate immunity.
MCDB 135. Cellular Growth Control and Oncogenesis
(4) THROWER
Prerequisite: MCDB 101A-B with a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 138.
Focuses on mechanisms of growth control of eukaryotes. Topics include: the properties of mammalian cells in culture and how they relate to malignant cells, growth factors and their receptors, cell cycle control, oncogenes and tumor suppressor genes.
MCDB 135H. Cellular Growth Control and Oncogenesis - Honors
(1) FOLTZ
Prerequisite: Concurrent enrollment in MCDB 135; consent of instructor.
Enrollment Comments: Quarters usually offered: Spring.
Honors section designed to permit an in-depth analysis of topics relating to Cellular Growth Control and Oncogenesis.
MCDB 136. Cytokine Action and Viral Pathogenesis
(2) SAMUEL
Prerequisite: MCDB 101B and 134 (134 can be taken concurrently); completion of both prerequisites with a grade of C or better; consent of instructor.
Enrollment Comments: Not open for credit to students who have completed MCDB 136H. Recommended for Honors students.
Virology course designed to permit an indepth consideration of selected aspects of the mechanisms of action of cytokines, with emphasis on the antiviral properties of interferons and their roles in host response to viral infection and viral pathogenesis.
MCDB 138. Medical Immunology
(4) SEARS
Prerequisite: MCDB 133 with a grade of C or better.
Interplay between the immune system and human disease is mechanistically evaluated by examining protective immunity against parasites and cancer, and immune dysfunction in transplantation, allergic, and autoimmune diseases, and AIDS. Computer exercises evaluate medical, case-based studies of human immune disorders.
MCDB 139. Medical Microbiology
(4) STAFF
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B, and EEMB 3. Completion of all prerequisitewith a grade of C or better.
Enrollment Comments: Not open for credit to students who have completed Biology 129.
Study of the characteristics of bacteria and viruses, both pathogenic and adventitious, as they are associated with diseases of humans.
MCDB 140L. Recombinant DNA Methods
(4) SMITH, S. LOW
Prerequisite: MCDB 101A-B and 110; or MCDB 101A-B and MCDB 108A-B-C (MCDB 108C may be taken concurrently); or MCDB 101A-B and MCDB W 108A and MCDB 108B-C (MCDB 108C may be taken concurrently). Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Quarters usually offered: Spring. Not open for credit to students who have completed Biology 132.
Basic techniques of molecular cloning. Screening of recombinant cDNA libraries, polymerase chain reaction, restriction endonucleases, gel electrophoresis, DNA sequencing, nucleic acid hybridization.
MCDB 145. Post-translational Protein Processing
(4) WAITE
Prerequisite: MCDB 108A or MCDB W 108A or Chemistry 142A with a grade of C or better.
Enrollment Comments: Quarters usually offered: Spring. Same course as Chemistry 151.
Structure/function relationships in interesting macromolecules isolated from marine organisms. Focus is on well-characterized pathways from horseshoe crabs, abolones, mussels, and fish as well as others.
MCDB 146. Stem Cell Biology in Health and Disease
(4) CLEGG
Prerequisite: MCDB 101A OR EEMB 129 with a minimum grade of C; and, MCDB 103 OR MCDB 112 with a minimum grade of C.
Enrollment Comments: Students must have a cumulative 3.0 for the proceeding 2 quarter(s). Designed for majors. Concurrently offered with MCDB 246. Quarters usually offered: Spring.
Basic biology of embryonic and adult stem cells and nuclear transfer, with emphasis on latest findings from the current literature.
MCDB 149. Mariculture for the 21st Century: Research Frontiers
(4) STAFF
Prerequisite: Upper-division standing.
Enrollment Comments: Not open for credit to students who have completed Biology 149. Same course as EEMB 149.
Recent progress and new directions in research increasing production of valuable marine animals, plants, and microorganisms. Control of reproduction, development, growth and disease in marine species; problems encountered in commercializing production; regional and biological solutions; the role of modern biotechnology.
MCDB 151. Neurobiology I: Cellular Organization and Biophysics of the Nervous System
(4) VANDENBERG, MA
Prerequisite: MCDB 1A and 1B. Completion of both prerequisites with a grade of C or better.
Enrollment Comments: Not open for students who have completed Biology 105 or MCDB 114 for a C or better.
Repeat Comments: MCDB 151 is a legal repeat of MCDB 114.
Properties of the nervous system ranging from single cells to the whole organism, using examples from vertebrates and invertebrates studied in terms of morphology, physiology, and behavior.
MCDB 151H. Neurobiology 1: Cellular Organization and Biophysics of the Nervous System - Honors
(1) VANDENBERG, MA
Prerequisite: Concurrent enrollment in MCDB 151; consent of instructor.
Honors section designed to permit an indepth analysis of topics relating to the properties of the nervous system ranging from single cells to the whole organism, using examples from vertebrates and invertebrates studied in terms of morphology, physiology, and behavior.
MCDB 152. Neurobiology II: Molecular and Cellular Neurobiology
(4) KOSIK, CLEGG
Prerequisite: MCDB 1A-1B and MCDB 151; completion of all prerequisites with a grade of C or better.
This second course of a three quarter neurobiology course sequence (151/152/153) covers both top down systems level approaches and bottom up molecular approaches to major topics in neurobiology. These topics include mechanisms of sensory transduction in at least two selected sensory systems, processing of sensory information within the brain, mechanisms of muscle control, cell signaling, neuronal plasticity, neuronal polarity, and the mapping of neural information to the brain.
MCDB 152H. Neurobiology II: Molecular and Cellular Neurobiology - Honors
(1) KOSIK, CLEGG
Prerequisite: Concurrent enrollment in MCDB 152; consent of instructor.
Honors seminar designed to permit an indepth consideration and analysis of both top down systems level approaches and bottom up molecular approaches to major topics in neurobiology. These topics include mechanisms of sensory transduction in at least two selected sensory systems, processing of sensory information within the brain, mechanisms of muscle control, cell signaling, neuronal plasticity, neuronal polarity, and the mapping of neural information to the brain.
MCDB 153. Neurobiology III: Developmental Neurobiology
(4) FEINSTEIN
Prerequisite: MCDB 1A-1B; and, MCDB 101A or EEMB 129; completion of all listed prerequisites with a grade of C or better.
Recommended Preparation: MCDB 112.
Enrollment Comments: Not open for credit to students who have completed Biology 106 or MCDB 115. (However, legal repeat policy applies).
Repeat Comments: MCDB 153 is a legal repeat of MCDB 115.
The course begins with fertilization and moves through sequential stages in the development of the nervous system, including cell migration and differentiation, axon outgrowth and pathfinding, programmed cell death, synaptogenesis, learning, memory, neurodegenerative conditions and current strategies for neuronal regeneration.
MCDB 153H. Neurobiology III: Developmental Neurobiology - Honors
(1) FEINSTEIN
Prerequisite: Concurrent enrollment in MCDB 153; consent of instructor.
Honors section designed to permit an indepth consideration and analysis of selcted topics relating to the development, maintenance, degeneratation and regeneration of the nervous system.
MCDB 161L. Research Immersion in Molecular Biosciences
(6) POOLE
Recommended Preparation: At least two upper division courses in any of the following areas: genetics, biochemistry, cell biology, development, physiology with a grade of B or better.
Enrollment Comments: Designed for majors. Quarters usually offered: Summer.
Intensive laboratory course covering basic approaches to biomedical research using model systems. Students will learn laboratory techniques as well as hypothesis building, experimental design, data analysis and data presentation.
MCDB 182. Introduction to Health Care and Biomedical Technology
(3) STAFF
Prerequisite: Upper-division standing.
Enrollment Comments: Same course as Engineering 182. Students must have a 3.0 grade-point average.
Course offered in conjunction with Sansum-SB Clinic and Cottage Hospitals and involves a series of lectures/discussions dealing with various aspects of health care delivery and modern biotechnology. Students also spend a period of time working with a physician or medical research scholar.
MCDB 183. Introduction to Teaching in Biology
(1-5) STAFF
Prerequisite: Upper-division standing and consent of instructor.
Enrollment Comments: May be repeated for credit to a maximum of 5 units. may not be applied toward the major.
Students will assist instructor in teaching course in which the student previously received a grade of A- or better. Activities will be determined in consultation with the instructor and may include leading discussion, laboratory, or tutorial section(s), attending lectures, and grading exams.
MCDB 184. Internship in Biological Sciences
(1-5) STAFF
Prerequisite: Upper-division standing; instructor and departmental approval required.
Enrollment Comments: Students must have a 2.5 cumulative grade-point average. may be repeated for credit to a maximum of 15 units, but no units may be applied toward the major (except Aquatic Biology, see restrictions in major narrative).
Opportunity to obtain practical biological-related research experience by working under faculty direction as an intern with local, state, federal, or private agencies. A written report will be submitted for evaluation.
MCDB 186. Research Colloquium in Biological Sciences
(1) STAFF
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B, and EEMB 3. Completion of all prerequisitewith a grade of C or better.
Enrollment Comments: May be repeated for credit in combination with Biology 195 and BMB 171 to a maximum of 3 units.
Lectures by UCSB faculty from various departments focused on their current research in a variety of biological disciplines.
MCDB 187. Pharmacology Colloquia
(1) WILSON, THROWER
Prerequisite: MCDB 1A, EEMB 2 and MCDB 1B, and EEMB 3 with a minimum grade of C or better in each prereq course.
Enrollment Comments: May be repeated for credit to a maximum of 4 units, but only 2 units may be applied toward the major.
Research seminars on current research topics in pharmacology presented by invited speakers.
MCDB 188. Literature in Plant Molecular Biology
(1) FINKELSTEIN, CHRISTOFFERSEN
Prerequisite: Consent of instructor.
Enrollment Comments: Quarters usually offered: Winter, Spring, Fall. Not open for credit to students who have completed Biology 168.
Critical reading and presentation of the current literature in plant molecular biology, cell biology and development.
MCDB 192. Special Topics
(1-4) STAFF
Prerequisite: Chem 1A-B-C with a minimum grade of C; MCDB 1A-B and EEMB 2 with a minimum grade of C. Upper-division standing in EEMB or MCDB and consent of instructor or department.
Enrollment Comments: May be repeated for credit in combination with Biology 192 and EEMB 192. Maximum units for credit in major: 8 for B.S.; 4 for B.A.
Special topics of current importance in biological sciences. Course content will vary. Information may be obtained in department office.
MCDB 194AAZZ. Group Studies for Advanced Students
(2) STAFF
Prerequisite: Upper-division standing and consent of instructor.
Enrollment Comments: May be repeated for credit in combination with Biology 194AA-ZZ and EEMB 194AA-ZZ to a maximum of 8 units. Individual letter designations may be repeated for credit to a maximum of 4 units. Maximum units for credit in major: 8 BS; 4 BA. See also credit limits with other courses in description of major requirements.
Oral reports by students.
MCDB 194A. Biochemistry-Molecular Biology
MCDB 194B. Biochemistry-Molecular Biology
MCDB 194BC. Biochemistry/Molecular Biology
MCDB 194BG. Bacterial Genetics.
MCDB 194CM. Cellular Microbiology
MCDB 194DM. Molecular Marine Biology and Marine Biotechnology
MCDB 194DS. Molecular and Cellular Immunobiology.
MCDB 194DT. Cell Cycle Regulation
MCDB 194DV. Developmental Biology
MCDB 194DY. Group Studies for Advanced Students
MCDB 194EO. Genetics
MCDB 194H. Group Studies for Advanced Students
MCDB 194HG. Group Studies for Advanced Students
MCDB 194KF. Science for the Common Good
MCDB 194KK. Clinical Research
MCDB 194MD. Underserved Medicine
MCDB 194MP. Microbial Pathogenesis
MCDB 194MR. Introduction to Microscopy for the Bio-sciences
MCDB 194PJ. Introduction to Hematology
MCDB 194RF. Plant Development Genetics
MCDB 194SB. Synthetic Biology
MCDB 194TW. Molecular mechanisms of human disease
MCDB 194V. Mycology
MCDB 194X. Cell Biology
MCDB 194ZM. Cell Biology Topics
MCDB 197. Directed Studies.
(1-5) STAFF
Prerequisite: MCDB majors only; and, consent of instructor and department; and upper- division standing; and, two upper-division courses in MCDB or EEMB.
Enrollment Comments: Students must have a minimum grade-point average of 2.5 in upper-division major courses and are limited to 5 units per quarter and 30 units total in all 197/198/199/199RA courses combined. Maximum units for credit defined on major sheets. See also credit limits with other courses in description of major requirements.
Hours and credit by arrangement with any faculty member.
MCDB 198. Directed Readings
(1-5) STAFF
Prerequisite: MCDB majors only; and, consent of instructor and department; and upper- division standing; and, two upper-division courses in MCDB or EEMB.
Enrollment Comments: Students must have a minimum grade-point average of 3.0 in upper-division major courses and are limited to 5 units per quarter and 30 units total in all 98/99/198/199/199AA-ZZ courses combined. Maximum units for credit in major: 8 BS; 4 BA. See also credit limits with other courses in description of major requirements.
Individual conferences one hour every two weeks. special readings designed to broaden the outlook of students and to knit into a cohesive whole the basic principles underlying the major disciplines in the field.
MCDB 199. Independent Studies
(1-5) STAFF
Prerequisite: MCDB majors only; and, consent of instructor and department; and upper-division standing; and, two upper-division courses in MCDB or EEMB.
Enrollment Comments: Students must have a minimum grade-point average of 3.0 in upper-division major courses and are limited to 5 units per quarter and 30 units total in all 98/99/198/199/199AA-ZZ courses combined. Maximum units for credit in major: 8 BS; 4 BA. See also credit limits with other courses in description of major requirements. Tutorial, 1-3 hours; field, 1-5 hours.
Hours and credit by arrangement with any faculty member. Laboratory or field.
Collapse Courses Graduate 
MCDB 203. Cell Biology
(4) MARTH, MA
Prerequisite: MCDB 1A-AL or MCDB 1B-BL or EEMB 2-2L, or equivalents.
Enrollment Comments: Quarters usually offered: Winter.
Introduction to the structure and function of cell organelles: membranes, nucleus, mitochondria, chloroplasts, endoplasmic reticulum, Golgi apparatus, lysosomes, microbodies, microtubules, cilia, centrioles, and microfilaments.
MCDB 212. Molecular Virology
(5) SAMUEL
Prerequisite: MCDB 108A-B-C and 101A-B or equivalent.
Consideration of selected animal viruses in terms of structure, mechanism of genetic expression, and effects of viral gene expression on cell function, as well as aspects of the virus-host interaction including viral persistence, interference, and interferon.
MCDB 220A. Chromosomes and Cell Cycle
(2) STAFF
Prerequisite: Graduate standing.
Structure and organization of the nucleus, chromatin and chomosome structure, organization, and function; DNA replication and replication origins; eukaryotic cell cycle regulation.
MCDB 220B. The Cytoskeleton
(2) WILSON
Prerequisite: Graduate standing.
Structure and function of the eukaryotic cytoskeleton. Structure and function of microtubules, microfilaments, and intermediate filaments.
MCDB 220C. From RNA to Membranes
(2) KOSIK, MA
Prerequisite: Undergraduate biochemistry (e.g., MCDB 108A-B-C or Chemistry 142A-B-C) and genetics (e.g., MCDB 101A).
Enrollment Comments: Concurrently offered with BMSE 220C. Quarters usually offered: Winter.
Structure and dynamics of biological membranes and membrane proteins, protein translocation and sorting in the endomembrane system of eukaryotic cells, extracellular matrix protein structure/function, cell-matrix and cell-cell interactions, cell adhesion receptors, transmembrane signaling by cell adhesion receptors.
MCDB 220D. Experimental Cytology and Digital Imaging
(4) FISHER
Prerequisite: Consent of instructor.
Introduction to imaging cellular substructure with the light microscope. Students receive theoretical and hands-on experience in obtaining maximum data from biological specimens using optical and digital enhancement techniques.
MCDB 221. Preparation and Evaluation of Research Proposals
(2) FOLTZ
Prerequisite: Graduate standing.
Instruction in preparation writing, and evaluation of research grant proposals.
MCDB 222. Sequence Analysis
(2) POOLE
Prerequisite: Consent of instructor.
Analysis of DNA and protein sequence data. Topics include protein property prediction, defining sequence similarity, sequence comparison, and sequence database searching.
MCDB 223. Signal Transduction
(2) BELLESTER, MAHAN
Prerequisite: Graduate standing.
A cell's growth is controlled by positive and negative cues from its surroundings. We will discuss the cell's signaling mechanisms that recognize these cues and initiate an intracellular set of events that generates a response.
MCDB 225. Development
(2) FOLTZ, FNKL., DT., POOLE, SMTH
Prerequisite: Graduate standing.
The molecular mechanisms of pattern formation and cellular differentiation that underlie developmental processes in a variety of important model systems.
MCDB 226A. Basic Pharmacology
(4) THROWER
Prerequisite: Consent of instructor.
Enrollment Comments: Quarters usually offered: Fall.
History and scope of pharmacology as a basic science; principles of drug action and relationship of pharmacology to physiology, chemistry, biochemistry emphasized.
MCDB 226AL. Pharmacology Lab I
(4) STOYAN, THROWER
Prerequisite: Concurrent enrollment in MCDB 226A.
Enrollment Comments: Not open for credit to students who have completed Biology 219AL.
Analysis of drug sites and mechanisms of action using isolated tissues, organs, and intact animal preparations.
MCDB 226B. Basic Pharmacology
(4) VANDENBURG
Prerequisite: Consent of instructor.
Enrollment Comments: Not open for credit to students who have completed Biology 219B.
Receptor signalling mechanisms; pharmacology of neurotransmitter and hormone receptors; molecular and cellular mechanisms of drug-receptor interactions.
MCDB 226C. Basic Pharmacology: Principles and Chemotherapy
(4) WILSON, THROWER
Prerequisite: Consent of instructor.
Enrollment Comments: Quarters usually offered: Spring.
Fundamental principles of pharmacology, drug-receptor theory, biochemical mechanisms of action of drugs.
MCDB 229. Protein Biochemistry
(2) WAITE
Prerequisite: Graduate standing.
Enrollment Comments: Same course as BMSE 229.
Discussion topics relevant to structure-function relationships in proteins including the chemical reactivity of amino acid side chains, posttranslational modifications, and the covalent and noncovalent interactions of multimeric structures. Case studies involve recent advances in structure-function relationships of mechanoproteins.
MCDB 230. Gene Regulation
(2) LOW, SAMUEL, HAYES
Prerequisite: Graduate standing.
Mechanisms and regulation of transcription in prokaryotic and eukaryotic organisms and their viruses.
MCDB 231. General Microbiology
(4) COOPER
Prerequisite: MCDB 1A-AL or MCDB 1B-BL or EEMB 2-2L; Chemistry 107A-B and 108, or Chem 130A-B-C, or Chem 109A-B-C.
Enrollment Comments: Quarters usually offered: Fall.
Introduction to biological properties of microrganisms historical foundations of the field of microbiology; a study of major groups of microorganisms, their structure, physiology, cultivation, and pathogenicity.
MCDB 232. Bacterial Pathogenesis
(3) MAHAN
Prerequisite: MCDB 101A-B.
Enrollment Comments: MCDB 231 recommended. Not open for credit to students who have completed Biology 228.
The mechanisms by which bacterial pathogens cause disease. Investigation ofthe bacterial gene products produced during infection to understand the metabolic, physiological, and genetic factors that contribute to the virulence of bacterial pathogens.
MCDB 233. Molecular and Cellular Immunobiology
(3) SEARS
Prerequisite: MCDB 101A-B, 108A-B-C or equivalent.
Enrollment Comments: Not open for credit to students who have completed Biology 223.
Introduction to, and evaluation of, the current concepts of immunology. Emphasis on immunoglobulin structure and function, cell-cell cooperation in the immune response, and the role of the major histocompatibility complex in regulating immune responsiveness.
MCDB 235. Experimental Strategies in Molecular Genetics
(1) WEIMBS, POOLE, CHRISTOF.
Prerequisite: Undergraduate biochemistry (MCDB 108A-B-C) and genetics (MCDB 101A-B).
Discussion of experimental strategies used to purify, analyze, and manipulate nucleic acids, isolate molecular clones from complex genomes, physically map genomes, analyze gene expression, and perform reverse genetics.
MCDB 238. Angiogenesis in Health and Disease
(2) GOTTSTEIN
Enrollment Comments: Quarters usually offered: Winter.
Principles and processes of physiological and pathophysiological angiogenesis and the specifics of tumor angiogenesis. Implications for diagnosis and therapy of cancer will be discussed.
MCDB 239. Cellular Microbiology
(4) STAFF
Prerequisite: Graduate standing.
Enrollment Comments: Same course as BMSE 239.
Exploration of the mechanisms by which microbes and their eukaryotic hosts interact at the cellular and molecular levels. Focus is on experimental strategies to investigate these interactions and primary literature is discussed.
MCDB 245. Post-Translational Protein Processing
(4) WAITE
Prerequisite: MCDB 108A or MCDB 218A or Chemistry 142A or equivalent.
Enrollment Comments: Same course as Chemistry 251.
Structure/function relationships in interesting macromolecules isolated from marine organisms. Focus is on well-characterized pathways from horseshoe crabs, abalones, mussels, and fish as well as others.
MCDB 246. Stem Cell Biology in Health and Disease
(4) CLEGG
Enrollment Comments: Graduate Course. Qualified undergraduate students may petition to enroll with instructor approval.
Basic biology of embryonic and adult stem cells and nuclear transfer, with emphasis on latest findings from the current literature.
MCDB 247. Social Dimensions of Stem Cell Research
(2) STAFF
Enrollment Comments: Open to non-majors. Quarters usually offered: Spring.
Overview of ethical, social and legal contexts of biological research with special reference to stem cells, embryology and policy.
MCDB 249. Mariculture: Research Frontiers in Farming the Sea
(4) STAFF
Prerequisite: Graduate standing.
Enrollment Comments: Same course as EEMB 249. Not open for credit to students who have completed Biology 249.
Recent progress and new directions in research increasing production of valuable marine animals, plants and microorganisms. Control of reproduction, development, growth and disease in marine species; problems encountered in commercializing production; regional and biological solutions; the role of modern biotechnology.
MCDB 251. Neurobiology I: Cellular Organization and Biophysics of the Nervous System
(4) MA, VANDENBERG
Prerequisite: MCDB 1A and 1B or equivalent. Completion of both prerequisites with a grade of C or better.
Enrollment Comments: Quarters usually offered: Fall.
Nervous system properties ranging from single cells to whole organisms, using examples from vertebrates/invertebrates studied in terms of morphology, physiology, behavior.
MCDB 252. Neurobiology II: Molecular and Cellular Neurobiology
(4) KOSIK, CLEGG
Prerequisite: MCDB 251 with a grade of B or better.
This second course of a three quarter neurobiology course sequence (251/252/253) will cover both top down systems level approaches and bottom up molecular approaches to major topics in neurobiology. These topics include mechanisms of sensory transduction in at least two selected sensory systems, processing of sensory information within the brain, mechanisms of muscle control, cell signaling, neuronal plasticity, neuronal polarity, and the mapping of neural information to the brain.
MCDB 253. Neurobiology III: Developmental Neurobiology
(4) FEINSTEIN
Prerequisite: MCDB 1A-1B; and, MCDB 101A or EEMB 129.
Recommended Preparation: MCDB 112.
Enrollment Comments: Quarters usually offered: Spring.
This course begins with fertilization and moves through sequential stages in the development of the nervous system, including cell migration and differentiation, axon outgrowth and pathfinding, programmed cell death, synaptogenesis, learning, memory, neurodegenerative conditions and current strategies for neuronal regeneration.
MCDB 260. Research Seminar in Biochemistry-Molecular Biology
(1) STAFF
Prerequisite: Graduate standing.
Seminars on research in progress presented by faculty of the Department of Chemistry and Department of Molecular, Cellular and Developmental Biology.
MCDB 261. Literature in Immunology
(1) SEARS
Prerequisite: Consent of instructor.
Critical reading and presentation of recent literature in immunology.
MCDB 262. Research Progress in Molecular, Cellular and Developmental Biology
(1) STAFF
Research presentations by postdoctoral fellows and advanced Ph.D. students of research progress in the department.
MCDB 263. Progress in Biochemistry and Molecular Biology
(1) STAFF
Research seminars presented by invited speakers on current research topics.
MCDB 265. Literature in Virology
(1) SAMUEL
Prerequisite: Graduate standing and consent of instructor.
Critical reading and presentation of the recent literature on animal viruses and host cells by graduate students, postdoctoral fellows, and staff.
MCDB 266. Literature in Neurobiology
(1) VANDENBERG, CLEGG, FEINST., MA
Prerequisite: Consent of instructor.
Critical reading and presentation of the literature in modern neurobiology.
MCDB 268. Literature in Plant Molecular Biology
(1) STAFF
Prerequisite: Graduate standing.
Critical reading and presentation of the current literature in higher plantmolecular biology, cell biology, and development.
MCDB 269. Pharmacology Colloquia
(1) WILSON, THROWER
Prerequisite: Graduate standing.
Enrollment Comments: Quarters usually offered: Spring.
Research seminars on current research topics in pharmacology presented by invited speakers.
MCDB 290AAZZ. Group Studies
(2) STAFF
Prerequisite: Consent of instructor.
Presentation and discussion of current research, to be selected from the following list. (see individual letter designations)
MCDB 290A. Research in Molecular Marine Biology
MCDB 290B. Research in Biomineralization
MCDB 290C. Studies in Regualtion of Cell Proliferation
MCDB 290CC. Centromeres and Chromosomes--Models and Analysis
MCDB 290CE. C Elegans Development
MCDB 290CS. Advanced Topics in Chromosome Segregation
MCDB 290DN. Developmental Neurobiology
MCDB 290ER. Epithelial Cell Biology and Molecular Renal Pathobiology
MCDB 290JM. Topics at the Interface of the Physical and Biological Sciences
MCDB 290LW. Microtubule Dynamics and Functions
MCDB 290MM. Bacterial Pathogenesis
MCDB 290MR. Introduction to Microscopy for the Bio-sciences
MCDB 290NB. Neurobiology
MCDB 290PM. Molecular Plant-Microbe Interactions
MCDB 290RF. Group Studies
MCDB 290S. Molecular Virology and Interferon Action
MCDB 290SF. Group Studies
MCDB 290SK. Research in Retinal Cell Biology
MCDB 290V. Current Research on Cell and Developmental Biology of Fungi
MCDB 290VA. Molecular Neurobiology: Ion Channels
MCDB 293. Computational Methods in Biochemistry-Molecular Biology
(1) CHRISTOFFERSEN
Prerequisite: Graduate standing.
Survey of computational methods in molecular biology. Topics include analysis and presentation of data, database searching, quantitative image analysis, and protein homology modeling. Emphasis on utilizing accessible software tools that are designed for nonprogrammers.
MCDB 500. Teaching Assistant Orientation
(1) STAFF
Prerequisite: Required of all teaching assistants.
Enrollment Comments: No unit credit allowed toward advanced degree. May be repeated for credit in combination with Biology 500.
General orientation regarding the University of California and the Santa Barbara campus; various pertinent regulations, officials and their functions, staff and functions; services available to teaching assistants and to students. Prospective teaching assistants are encouraged to take this course during the fall quarter prior to their employment.
MCDB 501. Practicum in Instruction
(1-4) STAFF
Prerequisite: Concurrent teaching assistant employment.
Enrollment Comments: No unit credit allowed toward advanced degree. May be repeated for credit in combination with Biology 501.
Practical experience in teaching within specified areas of biology. Students will have responsibility for one or more laboratory and/or discussion sections. Staff will periodically observe teaching assistants in actual teaching situations. Evaluation forms will be completed by members of the class sections.
MCDB 502. Techniques of Teaching and Laboratory Class Supervision
(1-2) STAFF
Prerequisite: Concurrent teaching assistant employment.
Enrollment Comments: Required of all teaching assistants. No unit credit allowed toward advanced degree. May be repeated for credit in combination with Biology 502.
Weekly discussion and readings on techniques of teaching including lecturing, leading discussions, writing and grading exams, student- teacher interactions, classroom dynamics, and teaching philosophy.
MCDB 503. Research Practium in Biology
(1-2) STAFF
Enrollment Comments: May be repeated for credit in combination with Biology 503.
Basic procedures and methods of research in a specific area as determined by consultation between the supervising faculty member and the research assistant. Includes weekly meetings and consultations, and formal evaluations.
MCDB 595AAZZ. MCDB Literature Seminar
(2) STAFF
Prerequisite: Consent of instructor.
Enrollment Comments: May be repeated for credit to a maximum of 36 units. Individual letter designations may be repeated for credit to a maximum of 36 units.
A critical review of research in selected fields of biology. Subject matter for these seminars will be selected from the following list: (refer to individual letter designations.)
MCDB 595A. Biochemistry-Molecular Biology
MCDB 595B. Biochemistry-Molecular Biology
MCDB 595BC. Biochemistry/Molecular Biology
MCDB 595BE. Biochemistry and Molecular Cell Biology for Engineers
MCDB 595BG. Bacterial Genetics
MCDB 595CM. Cellular Microbiology
MCDB 595DM. Molecular Marine Biology and Marine Biotechnology
MCDB 595DS. Molecular and Cellular Immunology
MCDB 595DV. Developmental Biology
MCDB 595EO. Genetics
MCDB 595F. General Physiology
MCDB 595G. Virology
MCDB 595KK. Clinical Research
MCDB 595MM. Contemporary Topics in Biochemistry and Molecular Biology
MCDB 595MP. Microbial Pathogenesis
MCDB 595MS. Group Studies
MCDB 595NN. Literature in Eukaryotic Molecular Genetics
MCDB 595RF. Group Studies
MCDB 595SF. Group Studies
MCDB 595V. Mycology
MCDB 595X. Cell Biology
MCDB 596. Directed Reading and Research
(2-12) STAFF
Prerequisite: Consent of instructor.
Hours and credit by arrangement with faculty.
MCDB 597. Individual Study for Master's Comprehensive Examinations and Ph.D. Examinations
(1-12) STAFF
Prerequisite: Consent of instructor.
Enrollment Comments: No unit credit allowed toward advanced degree. Students are limited to 24 units per examination, and 12 units per quarter. May be repeated for credit in combination with Biology 597.
Individual study for M.A. comprehensive examinations and Ph.D. examinations.
MCDB 598. Master's Thesis Research and Preparation
(1-12) STAFF
Prerequisite: M.A. (thesis) candidate and consent of committee chair.
Enrollment Comments: May be repeated for credit in combination with Biology 598 to a maximum 12 units. No unit credit is allowed toward advanced degree.
For research underlying the thesis and writing of the thesis.
MCDB 599. Ph.D. Dissertation Preparation
(1-12) STAFF
Prerequisite: Ph.D. candidate and consent of instructor.
Enrollment Comments: May be repeated for credit in combination with Biology 599 to a maximum of 12 units.
For writing of the dissertation.

 
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MCDB W 108A. General Biochemistry
(4) SEARS
Prerequisite: MCDB 1A, and EEMB 2 and MCDB 1B; and Chemistry 1A-B-C; and Chemistry 109A-B- C (Chem 109C may be taken concurrently). Completion of all listed prerequisites with a grade of C or better.
Enrollment Comments: Quarters usually offered: Summer. Not open for credit to students who have completed Biology 108A. Not open for credit to students who have completed MCDB 108A.
Repeat Comments: Students needing to repeat MCDB W 108A due to a poor grade the first time, can repeat it either as MCDB 108A or MCDB W 108A. Only one repeat attempt between the 2 courses is allowed.
Introduction to the structures and functions of proteins, including enzymes, with emphasis on their basic architecture and biological mechanisms of action and regulation. Methods used for characterizing proteins and analyzing enzyme kinetic data are also emphasized.